Enterocutaneous Fistulas

Enterocutaneous fistulas (ECF) are serious complications associated with high morbidity and mortality. Most ECF occurs after surgery or trauma, while other times Crohn's disease, necrotizing enterocolitis, intra-abdominal abscess, malignant disease and radiotherapy are the culprits. ECF can be classified as low output (less than five ml/kg/day), or high output (greater than five ml/kg/day). Postoperative ECF results from infection and breakdown of an anastomosis, bowel injury, deserosalization of bowel, suture-lines defects, tight sutures with ischemic necrosis, injury to mesenteric vessels, poor hemostasis, adhesive ischemia, volvulus and bowel loop caught in a fascial suture. Postoperative ECF can be also classified as early (those that occur within 48 hours after surgery and are associated to a technical error), and late (occurring 48 hours after the procedure) and associated with low ischemia time. It is vital to identify the source and route of the ECF tract by imaging techniques (UGIS, Barium enema, CT Scan or MRI) and whether the patient has distal obstruction. Management consists of reducing the septic state by adequate draining, hydration, correction of electrolyte imbalances, parenteral antibiotics, somatostatin-14 trial, bowel rest, parenteral nutrition, cutaneous protection, and surgical correction using resection with anastomosis or bypass procedures if the ECF fails to respond to conservative measures.


References:
1- Fekete CN, Ricour C, Duhamel JF, Lecoultre C, Pellerin D: Enterocutaneous fistulas of the small bowel in children (25 cases). J Pediatr Surg. 13(1):1-4, 1978
2- Lévy E, Frileux P, Cugnenc PH, Honiger J, Ollivier JM, Parc R: High-output external fistulae of the small bowel: management with continuous enteral nutrition. Br J Surg. 76(7):676-9, 1989
3- Falconi M, Pederzoli P: The relevance of gastrointestinal fistulas in clinical practice: a review. Gut 49: iv2-iv10, 2002 
4- Gonzalez-Pinto I, Moreno Gonzalez E: Optimizing the treatment of upper gastrointestinal fistulas. Gut 49: iv21-iv28, 2002
5- Jamil M, Ahmed U, Sobia H: Role of somatostatin analogues in the management of enterocutaneous fistulae. J Coll Physicians Surg Pak. 14(4):237-40, 2004
6- Ahmad RR, Fawzy SY: Enterocutaneous fistula. Causes and management. Saudi Med J. 28(9):1408-13, 2007


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